Clenbuterol is not an anabolic steroid, but a stimulant from the sympathomimetics group. This group contains compounds that most people are familiar with, including caffeine, ephedrine, albuterol, amphetamines, cocaine and so on. In fact, it is a large group of drugs that are all related to each other. All stimulants are similar and work the same way. The action of clenbuterol on the nervous system is manifested by its interaction with adrenergic receptors in various tissues and cells of the body. Due to the affinity of Clenbuterol for these receptors, various effects occur, depending on the type of tissue being stimulated. Particular attention is paid to the role of clenbuterol in adipose tissue.
There are two main types of adrenergic receptors in the body: alpha and beta receptors. Within these two different species there are 9 subtypes i.e. Alpha 1, Alpha 2, Beta 1, Beta 2, etc. Clenbuterol and other stimulants differ in their ability to stimulate different receptor subtypes. Clenbuterol has a strong selective stimulating effect on beta-2 adrenergic receptors and is therefore known as a beta-2 receptor agonist. Due to the activity of Clenbuterol on beta-2-adrenergic receptors, the process of fat loss begins with the release of free fatty acids (lipolysis). As a result, the drug is popular among bodybuilders and athletes, as well as celebrities and anyone who wants to lose weight.
It should be noted that long-term use of Clenbuterol reduces the response of beta-2 receptors to stimulation. The effects of addiction develop rapidly. The rate of fat burning decreases while you are taking this medicine until you completely stop losing fat. There are two ways to remove the citation effect. First, include a drug-free period (at least 2 weeks) into your schedule. Second, take the antihistamine ketotifen fumarate, which regulates beta-2 receptors.
How does Clenbuterol work?
There are two types of adrenergic receptors in adipose and muscle tissue, alpha and beta. The excitation of the first group of receptors promotes the active accumulation of body fat, while the second group regulates the work of the body so that it uses fats as a source of energy and significantly increases their rate of breakdown. Clenbuterol is a beta-2 agonist that stimulates beta-adrenergic receptors. Its use activates the mechanism of biochemical reactions that enhance lipolysis, the breakdown of fat into components.
In addition to burning fat, the drug speeds up metabolism, increasing its rate by 20-30%. This provides another definite advantage during drying. Lipoprotein lipase is more active when using Clenbuterol to prevent the formation of fats in the body. The use of this medication stimulates thyroid function to increase the production of fat-burning hormones. These properties of Clenbuterol are ideal for eliminating excess body fat.
This medicine, produced in the form of tablets, will be of great benefit to any athlete during the dry season. Accelerates metabolism and secretion of synthesized thyroid hormones. These and other effects can help you lose body fat on a low-calorie diet.
Effect of Clenbuterol
The main effect of taking Clenbuterol, which we have already mentioned, is powerful fat burning. Athletes take Clenbuterol and lose weight in competition to reduce the amount of subcutaneous fat while maintaining maximum muscle mass. However, it should be remembered that the drug is considered doping in bodybuilding, and its effect lasts in the body for 2-3 weeks.
Maple is also accepted in dry classes. Since the drug is non-hormonal and has no side effects like anabolic steroids, not only men but also women are affected. To achieve the desired effect, the use of Clenbuterol should be combined with rapid training and proper nutrition.
One of the benefits of Clenbuterol is that it not only burns fat but also has powerful anti-catabolic effects. Clenbuterol is also used in bodybuilding to protect damaged muscles during weight loss.
A small dose of exercise medication can improve their quality and thus increase the strength of the athlete. It has a clear weak anabolic effect. However, it lacks its catabolic properties and the ability to burn fat.
Useful properties for the athlete
To fully understand how Clenbuterol is used in bodybuilding, you need to know how the drug affects the body and what its benefits are:
- It helps burn subcutaneous fat. By contributing to cell proliferation, it promotes the biochemical reaction that triggers lipolysis – the breakdown of energy-releasing fat. Clenbuterol causes a strong release of adrenaline, which promotes fat loss.
- Fast Metabolism. Health studies confirm a 30% increase in metabolism. By increasing metabolism, the drug inhibits the activity of lipase, which is responsible for the process of storing fat.
- Muscles protect against injuries. Due to its anti-catabolic properties, it stops the breakdown of white eggs in the body muscles through continuous biochemical processes.
- A good and inexpensive review from athletes confirms that Clenbuterol does not have the same “effective weight”.
Mechanism of Action of Clenbuterol
Clenbuterol is a selective beta-2 agonist, structurally and pharmacologically similar to ephedrine and albuterol in that it dilates the bronchi, but has a more pronounced thermogenic and muscle-stimulating effect. This effect is due to the fact that, in addition to acting on the bronchi, it also acts on beta-2 receptors found in muscles, fat cells and the central nervous system. Therefore, its use as a dopant studies not only the respiratory system, but also muscle, adipose tissue, brain, and metabolism. Therefore, Clenbuterol is known in bodybuilding as a drug that increases energy and activates thermogenesis.
Clenbuterol is commonly used for training, pre-race and cutting. It is seldom used outside or during the muscle building phase. Some bodybuilders may use Clenbuterol during the (often successful) phase of muscle building to reduce fat storage over time while consuming more calories than usual. But it is basically a waste of time and money, because Clenbuterol does not have that pharmacological effect. As mentioned earlier, Clenbuterol binds to fat cell receptors and causes lipolysis, which causes free fatty acids to enter the bloodstream. Their compounds have to go through another phase of fat burning: oxidation. During this process, fatty acids move from the bloodstream to cells and mitochondria, where they oxidize, but not all fats entering the body taking in excess calories is lipolysis.
Clenbuterol can be used alone or in combination with other compounds. If the drug is used as monotherapy or in combination with other drugs it does not change the way it is used. The normal course of Clenbuterol is 2 weeks / 2 weeks rest (or 8 weeks ketotifen twice a week). To reduce the risk of side effects on the heart and other systems, it is recommended to take Clenbuterol for no more than 12 weeks.
After receiving the introductory medicine, you should study the course “Clenbuterol: application in bodybuilding”. The first dose on the first day is 0.02 mg. The daily intake is increased by 0.02 mg, from the sixth to the twelfth day the total consumption should be reduced to 0.12 mg of the drug, including the remaining unchanged – 0.12 mg. On day 13, the dose should be reduced to 0.08 mg. On the fourteenth day, stop taking the drug with an intake of 0.04 mg in bodybuilding, it should be taken in the morning, when the dose is increased, the intake is divided into two parts – in the morning and in the afternoon. In no case should you have it for the night – after studying the reviews of athletes, we can conclude that it will be about insomnia.
Of all the types of Clenbuterol, athletes usually choose pills because they are more convenient to use. Athletes need to know how to take Clenbuterol to avoid side effects. Attention should be paid to the dosage, as well as the rules for their combination with other drugs, in strict accordance with the instructions.
The course of Clenbuterol weight loss takes about two weeks. The body then adjusts to the effect of the medicine, so you should rest for at least 14 days. It is recommended that ketotifen be discontinued immediately. Without them, the notice period can last up to two months or longer.
For men, it is recommended to increase the dose gradually to 20 micrograms per day, gradually increasing to 100-120 micrograms. The dose has been reduced for the last two days as well.
For women, the diet is prepared on the same principle, but the average dose is less than 80-100 mcg.
Most athletes do not take Clenbuterol alone, but also combine it with other medications. The combined use of Clen and Ketotifen ensures that the receptors responsible for burning fat do not lose focus. Clenbuterol and ketotifen should be given in the afternoon.
Johimbin may increase the effect of the medicine by blocking the action of receptors on the body that build up body fat. Using Clen with Winstrol will not only lose weight but also gain muscle mass.
Anavar is a light steroid that can be used by both men and women. The combination of Clenbuterol does not add extra pounds and increases the effectiveness of the course.
L-Carnitine stimulates metabolism and significantly increases the effects of Clenbuterol in the same way. With Kakan, you can train more efficiently by increasing your energy intake.
Losing 4-8 kg in two weeks is considered a good result. The effectiveness of Clenbuterol depends on the individual characteristics of the body.
Clenbuterol side effects
Since Clenbuterol is not an anabolic steroid, it does not have the usual side effects of this drug class. At the same time, Clenbuterol has the characteristic side effects of all stimulants. Therefore, many of the side effects of Clenbuterol are quite similar to those caused by caffeine, ephedrine, and other stimulants. Abnormal personal problems with other stimulants can also occur with Clenbuterol.
Muscle cramps are often one of the most common side effects caused by Clenbuterol. A similar effect was observed with binding albuterol. The reason for the excretion of the amino acid taurine from the body is with Clenbuterol. Studies have shown that taurine levels in muscles and plasma decrease due to the use of Clenbuterol. Amino acids such as magnesium, potassium and sodium are essential for the regulation of neurotransmitters and neurotransmitters that control the contraction and relaxation of all muscle types. When stiffness is insufficient, seizures can lead to involuntary muscle spasms, often very severe and painful. Adding a dose of 2.5-5g per day to the turbine has been shown to help reduce complications.
Side effects of clenbuterol on the cardiovascular system include myocardial infarction, ventricular dilatation, and myocardial infarction. Taking Clenbuterol undoubtedly increases the load on the cardiovascular system, which should be taken into account by anyone who wants to take the drug to achieve anabolic effects.
Other Clenbuterol side effects include tremors, insomnia, high blood pressure, increased sweating, nausea, and headaches. Side effects of the drug include allergic reactions in the form of hives and rashes.